Good syndrome accompanied by pure red cell aplasia

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Pure Red Cell Aplasia Associated with Good Syndrome

Pure red cell aplasia (PRCA) and hypogammaglobulinemia are paraneoplastic syndromes that are rarer than myasthenia gravis in patients with thymoma. Good syndrome coexisting with PRCA is an extremely rare pathology. We report the case of a 50-year-old man with thymoma and PRCA associated with Good syndrome who achieved complete PRCA remission after thymectomy and postoperative immunosuppressive ...

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Myelodysplastic Syndrome with Erythroid Aplasia following Pure Red Cell Aplasia

Myelodysplastic syndrome (MDS) with erythroid aplasia is a very rare disorder that has not been clearly defined. We experienced a case of pure red cell aplasia (PRCA), which evolved to MDS with erythroid aplasia. A 59-year-old male with transfusion-dependent PRCA was referred to our hospital for an evaluation of newly developed thrombocytopenia. Two years ago, PRCA was diagnosed by the laborato...

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Acquired pure red cell aplasia.

Correspondence MEDICALTJOSRNAL 559 Acquired Pure Red Cell Aplasia SIR,-May we make the following observation about your article on acquired pure red cell aplasia and its treatment with steroids (6 April, p. 3) ? A pure red cell aplasia that responded to riboflavine or prednisone has been described in African adults and in children with marasmus and kwashiorkor.' In marasmus and kwashiorkor an e...

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Pure red cell aplasia associated with Good's syndrome accompanied by decreased stem cell factor production in the bone marrow.

A 79-year-old Japanese woman diagnosed with pure red cell aplasia (PRCA) associated with thymoma and hypogammaglobulinemia (Good's syndrome) was successfully treated with cyclosporine-A after a thymectomy. We further studied the etiology of this case. A burst-forming unit erythroid (BFU-E) assay with SCF restored erythropoiesis in vitro. SCF production was reduced in bone marrow stromal cells; ...

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A patient with pure red cell aplasia and Good's syndrome.

ma, and hypogammaglobulinemia,2,5-8 however, no patient, except ours, was given a diagnosis of Good’s syndrome. In our case, anemia improved in response to immunosuppressive agents as it did in most of the other cases,2,5-8 but an increased frequency of various infections was seen, since Good’s syndrome is an immunodeficiency condition. Thymectomy normalized erythropoiesis in 1 out of 2 cases.7...

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ژورنال

عنوان ژورنال: Interactive CardioVascular and Thoracic Surgery

سال: 2009

ISSN: 1569-9293

DOI: 10.1510/icvts.2009.210393